Nitrofungin is a broad-spectrum antimycotic agent. It is often used in dermatology to treat patients from nail fungus and skin. It is also suitable for the treatment of systemic mycoses and secondary bacterial infections that develop against the background of damage by pathogenic microflora. It contains a potent substance that has side effects and restrictions on use, so you should use it only after reading the instructions.
Release form and composition
Nitrofungin is produced by various pharmaceutical companies, such as IVAX Pharmaceuticals and TEVA affiliates in Israel and the Czech Republic. The active ingredient is chloronitrophenol. A transparent solution for external use is made from it. Additional elements that make up the drug are water, ethanol, and triethylene glycol.
Ethyl alcohol in the composition of Nitrofungin provides its disinfectant properties and enhances the effect of chloronitrophenol.
The drug looks like a viscous liquid of a yellowish or greenish tint. Since ethanol is present in the composition, a characteristic smell of alcohol emanates from the solution. The medicine is poured into glass bottles with a dropper, the volume of which is 25 ml. Nitrofungin is stored away from children, in places without direct sunlight and high temperatures. Optimum are 10-25 degrees above zero, at which the shelf life of the drug is five years.
Chloronitrophenol, which plays a key role in the composition of the drug, is a derivative of undecylenic acid. The substance works in two ways: it destroys pathogenic fungi and helps to cope with bacteria. Chloronitrophenol-based drugs are prescribed to combat gram-positive and gram-negative microorganisms, microsporia, trichophyton, candidiasis and some other pathogens of the fungus.
The component does not penetrate the systemic circulation and has only a local effect. The active substance fights against pathogenic cells, triethylene glycol promotes tissue healing and the formation of healthy particles. Due to the complex molecular composition, the drug exhibits both disinfectant and antimycotic properties.
Nitrofungin has a fungistatic and fungicidal effect. Depending on the concentration, the medication affects the further reproduction of the pathogen, gradually inhibiting it, or killing harmful cells. The active component is able to accumulate inside the treated tissues, thereby reducing the required frequency of use of the drug.
Indications and contraindications
Instructions for use Nitrofungin states that the solution is intended for the treatment of candidiasis of the skin, onychomycosis, foot fungus, rubrophytia, trichophytosis and infectious lesions of the auditory canal. Due to the lack of systemic effects on the body, the medication is contraindicated only for people who have individual intolerance to the components of the composition.
Many doctors believe that the solution is ineffective in dealing with nail damage, but clinical studies say different. Onychomycosis is a complex disease that can be cured by using Nitrofungin and oral antimycotics at the same time. Also, the success of therapy in this case should be discussed on the basis of the degree of neglect of the disease. With severe mycosis, even potent drugs can not cope with the problem.
However, Nitrofungin is primarily intended for the treatment of skin fungus. With the help of a medication, you can cure an infection that has appeared on the foot, between the fingers, in the nail bed. The drug works in any area of the foot, including on the heel. The components of the composition quickly penetrate into the deeper layers of the skin and act almost immediately on the pathogen.
The instruction warns of the possibility of developing side effects during treatment with Nitrofungin. They are limited to local reactions like burning and excessive dryness. Cases of photodermatitis have been reported. Unlike ointments, which are used to treat fungus, the solution should not get on healthy tissues.
If Nitrofungin has affected clean skin, it must be washed and greased with eucalyptus or vegetable oil. When a patient is swallowed, symptoms of poisoning are noted:
- excessive agitation;
- fainting state.
All this is accompanied by the release of urine in a green tint. Lack of medical care in this case will aggravate the situation.
If the product is applied to surfaces that have an increased pH, then its effectiveness will decrease. A similar situation is observed in contact with organics, such as body fluids.
The penetration of a large dose of Nitrofungin in the gastrointestinal tract provokes myocardial infarction, pulmonary edema, significant violations in the state of the liver and kidneys. To avoid such an outcome, it is necessary to timely wash the stomach and take enterosorbent drugs. If they are not at hand, then use vegetable oil.
How to treat a fungus with Nitrofungin
According to the instructions, the medication is acceptable for use by people who are already fifteen years old. The solution is used pointwise, treating the affected areas of the nail with liquid. With extensive lesions of the foot, they infiltrate a cotton pad, after which they wipe all infected areas.
The medication should not be diluted with water or other means. The exception is cases of pronounced irritation, but in such a situation it is more effective to change the drug than to reduce its concentration. The duration of therapy for onychomycosis and foot fungus is determined by the rate of disappearance of the symptoms of the disease. When the manifestations of the disease disappear, Nitrofungin will need to treat the skin and keratin plates three times a day twice a week.
If within 10 days there are no changes, then you need to consult a doctor. The specialist will diagnose and select another tool that will be more effective.
Cost and analogues
A bottle of medicine can be bought for 250-300 rubles. Nitrofungin Neo is considered as the main analogue. The drug is made from tridecanamine undecylenate. The tool is also produced in the form of a solution for external use. The drug is supplied to pharmacies in bottles of 25 or 30 ml. Excipients in its basis are similar to the composition of Nitrofungin.
Neo is considered a stronger version of the original drug. The medication is prescribed for:
- mycotic eczema;
- mixed infections of the ears and skin;
- mycoses of the auditory meatus;
- damage to the soles or interdigital space.
Nitrofungin Neo is not prescribed for children under two years of age and for patients with individual sensitivity to active components. It is not recommended to carry out treatment with the drug during the period of bearing or feeding the child. The medication can affect the healing of large wounds, so if they occur in the area of fungal infection, you should choose another medicine. Nitrofungin Neo sometimes provokes an exacerbation of eczematous or acute dyshidrotic epidermophytosis.
The medication is applied topically in small quantities until the symptoms disappear. It is permissible to use the product in order to prevent nail fungus. For this, the surface of the plates is treated with a solution for three weeks.
In pharmacies, Nitrofungin Neo costs from 270 rubles.
Reviews of patients using Nitrofungin from fungus
Anna, 34 years old.
The toenails were very yellow from the fungus, the doctor advised me to buy Nitrofungin. He was treated for a month, and then used for another week for prevention. Over time, the nails again became pink and dense.
Oleg, 23 years old.
I am sick with a fungus stably 3 times a year. Therefore, if I suddenly feel an itch between my fingers, I immediately smear Nitrofungin. The tool helps well, although the skin is dubbed from it. I would like to replace it with something else, but so far I can not find a suitable analogue in price and properties.